2014
The cardiac stem cell compartment is indispensable for myocardial cell homeostasis, repair and regeneration in the adult Journal Article
In: STEM CELL RESEARCH, vol. 13, no. 3, B, pp. 615-630, 2014, ISSN: 1873-5061.
The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation Journal Article
In: EUROPEAN HEART JOURNAL, vol. 35, no. 39, SI, pp. 2722-2731, 2014, ISSN: 0195-668X.
Absence of Evidence Is Not Evidence of Absence Pitfalls of Cre Knock-Ins in the c-Kit Locus Journal Article
In: CIRCULATION RESEARCH, vol. 115, no. 4, pp. 415-418, 2014, ISSN: 0009-7330.
Understanding Tissue Repair Through the Activation of Endogenous Resident Stem Cells Book Chapter
In: Humana Press, Cham (Ed.): pp. 31-48, Humana Press, Cham, 2014, ISBN: 978-3-319-03572-7.
Protection against doxorubicine-induced cardiomyopathy by bergamot polyphenols through myocyte survival and cardiac stem cell activation Journal Article
In: CARDIOVASCULAR RESEARCH, vol. 103, no. 1, 2014, ISSN: 0008-6363, (3rd Congress of the ESC-Council-on-Basic-Cardiovascular-Science on Frontiers in Cardio Vascular Biology, Barcelona, SPAIN, JUL 04-06, 2014).
Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy Journal Article
In: Journal of the American Heart Association, vol. 3, no. 2, pp. e000434, 2014.
2013
Adult c-kit(pos) Cardiac Stem Cells Are Necessary and Sufficient for Functional Cardiac Regeneration and Repair Journal Article
In: CELL, vol. 154, no. 4, pp. 827-842, 2013, ISSN: 0092-8674.
Sustained delivery of insulin-like growth factor-1/hepatocyte growth factor promotes endogenous cardiac repair and regeneration in the chronic ischemic heart Proceedings Article
In: pp. 277, 2013, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), Amsterdam, NETHERLANDS, AUG 31-SEP 04, 2013).
Sustained delivery of Insulin-Like Growth Factor-1/Hepatocyte Growth Factor promotes endogenous cardiac repair and regeneration in the chronic ischemic heart Proceedings Article
In: pp. E1141, 2013, ISSN: 0735-1097, (62nd Annual Scientific Session of the American-College-of-Cardiology, San Francisco, CA, MAR 09-11, 2013).
2012
Aging and Senescence of Endogenous Cardiac Stem Cells (eCSCs) Determines Their Growth and Differentiation Potential Proceedings Article
In: 2012, ISSN: 0009-7322.
Resident c-kit-positive Cardiac Stem Cells Replenish Cardiomyocytes During Physiological Cardiac Growth Proceedings Article
In: 2012, ISSN: 0009-7322.
Optimizing Cardiac Repair and Regeneration Through Activation of the Endogenous Cardiac Stem Cell Compartment Journal Article
In: JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, vol. 5, no. 5, SI, pp. 667-677, 2012, ISSN: 1937-5387.
c-kit-positive cardiac stem cells regulate physiological myocardial cell turnover and are not of bone marrow origin in the adult life Proceedings Article
In: pp. S46, 2012, ISSN: 0008-6363, (2nd Congress of the European-Society-of-Cardiology Council on Basic Cardiovascular Science - Frontiers in Cardiovascular Biology, London, ENGLAND, MAR 30-APR 01, 2012).
Activity status of resident adult cardiac stem cells determines their stem cell properties and growth kinetics Proceedings Article
In: pp. S15-S16, 2012, ISSN: 0008-6363, (2nd Congress of the European-Society-of-Cardiology Council on Basic Cardiovascular Science - Frontiers in Cardiovascular Biology, London, ENGLAND, MAR 30-APR 01, 2012).
Endogenous cardiac stem cell (eCSC) activation, myogenesis and angiogenesis contribute to cardiac remodelling following intensity-controlled exercise training Proceedings Article
In: pp. S16, 2012, ISSN: 0008-6363, (2nd Congress of the European-Society-of-Cardiology Council on Basic Cardiovascular Science - Frontiers in Cardiovascular Biology, London, ENGLAND, MAR 30-APR 01, 2012).
Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms Journal Article
In: HEART, vol. 98, no. 1, pp. 5-10, 2012, ISSN: 1355-6037.
2011
MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch In Vitro and Vascular Remodeling In Vivo Journal Article
In: CIRCULATION RESEARCH, vol. 109, no. 8, pp. 880-U146, 2011.
In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 58, no. 9, pp. 977-986, 2011, ISSN: 0735-1097.
Roles of Wnt/beta-catenin and Tgf-Beta1/Smad2 signaling pathways in endogenous resident c-kit-positive cardiac stem cell proliferation and cardiomyogenic specification in vitro Proceedings Article
In: pp. 957, 2011, ISSN: 0195-668X.
Adult myocardial cell regeneration originates from and is the progeny of endogenous resident c-kit-positive/CD45-negative cardiac stem cells Proceedings Article
In: pp. 957, 2011, ISSN: 0195-668X.
Resident adult cardiac stem cells fulfil Koch's postulates as the causative agents for myocardial regeneration and homeostasis Proceedings Article
In: pp. 959, 2011, ISSN: 0195-668X.
2010
Resident Adult Rat Cardiac Stem Cells Fulfill Koch's Postulates as the Causative Agents for Myocardial Regeneration and Homeostasis Proceedings Article
In: 2010, ISSN: 0009-7322.
Cardiac Stem Cell Activation and Ensuing Myogenesis and Angiogenesis Contribute to Cardiac Adaptation following Intensity-Controlled Exercise Training Proceedings Article
In: 2010, ISSN: 0009-7322.
2009
Distinct Roles of Wnt/beta-catenin and TGF-beta 1/Smad2 Signaling in Adult Cardiac Stem Cell Expansion and Specification in vitro Proceedings Article
In: pp. S809, 2009, ISSN: 0009-7322, (82nd Scientific Session of the American-Heart-Association, Orlando, FL, NOV 14-18, 2009).
c-kit+/cd45-cardiac stem cells generate polygonal stromal cells and secrete myxoid matrix in atrial myxomas Proceedings Article
In: pp. 152-153, 2009, ISSN: 0195-668X.
In situ activation of endogenous cardiac stem cells by intra-coronary administration of IGF-1 and HGF induces myocardial survival and regeneration in the infarcted pig myocardium Proceedings Article
In: pp. 459, 2009, ISSN: 0195-668X.
Use of heterologous non-matched Cardiac Stem Cells (CSCs) without immunosuppression as an effective regenerating agent in a porcine model of acute myocardial infarction Proceedings Article
In: pp. 495, 2009, ISSN: 0195-668X.
The role of endothelial progenitor and cardiac stem cells in the cardiovascular adaptations to age and exercise Journal Article
In: FRONTIERS IN BIOSCIENCE, vol. 14, pp. 4685-4702, 2009, ISSN: 1093-9946.
2008
Cardiac atrial myxomas originate from c-kit+/ flk-1+/Isl-1+/ Nkx2.5+cardiac stem and progenitor cells Proceedings Article
In: pp. 527, 2008, ISSN: 0195-668X.
Cardiomyogenesis from adult cardiac stem cells in response to the morphogens of the developing heart Proceedings Article
In: pp. 896, 2008, ISSN: 0195-668X.
2007
Cardiac stem cell ablation worsens cardiac remodeling and increases mortality after diffuse myocardial damage in rats Proceedings Article
In: pp. 228, 2007, ISSN: 0195-668X.
Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells Journal Article
In: JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 282, no. 15, pp. 11397-11409, 2007, ISSN: 0021-9258.
Resident cardiac stem cells Journal Article
In: CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 64, no. 6, pp. 661-673, 2007, ISSN: 1420-682X.
2006
Cardiac stem cell ablation blocks regeneration, exacerbates cardiac remodeling and increases mortality after diffuse myocardial injury. Proceedings Article
In: pp. 16, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).
Biological properties and regenerative potential, in vitro and in vivo, of human cardiac stem cells isolated from each of the four chambers of the adult human heart Proceedings Article
In: pp. 87, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).
The pig heart harbors cardiac stem-progenitor cells which respond to increasing growth factor stimulation regenerating the infarcted myocardium Proceedings Article
In: pp. 99, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).
Molecular signalling pathway determining cardiac stem cell fate Proceedings Article
In: pp. 188-189, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).
Statins foster cardiac stem cell activation and new myocyte formation after acute neurohumoral overload Proceedings Article
In: pp. 209, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).
Myocardial damage induces a growth factor Para/Autocrine loop in the spared myocytes which fosters cardiac stem cell activation and ensuing myocyte regeneration Proceedings Article
In: pp. 298, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).
The cardiac stem cell: The adult mammalian heart harbours oct-4(pos) cardiac stem cells with very broad developmental potential Proceedings Article
In: pp. 303, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).
HMG-CoA reductase inhibitors enhance cardiac stem-progenitor cell activation and new myocyte formation after diffuse myocardial damage Proceedings Article
In: pp. 18, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).
Wnt signaling and the polycomb-group gene Bmi-1 modulate cardiac stem cell fate Proceedings Article
In: pp. 20, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).
Human Cardiac Stem Cells: reproducible isolation and functional characterization of their in vitro and in vivo biological properties and regenerative potential Proceedings Article
In: pp. 161, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).
Exercise training activates cardiac stem/progenitor cells through the induction of growth factor production by the myocardium Proceedings Article
In: pp. 444, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).
The pig heart harbors cardiac stem-progenitor cells which respond to growth factor stimulation regenerating the infarcted myocardium Proceedings Article
In: pp. 546-547, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).
Cardiac stem cells expressing the pluripotency marker Oct-4 are present in the adult mammalian heart Proceedings Article
In: pp. 552, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).
In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 48, no. 2, pp. 417, 2006, ISSN: 0735-1097.
2005
Cardiac stem-progenitor cell resistance to hyper-adrenergic stimulation produces rapid left ventricular function recovery after isoproterenol-induced diffuse myocardial damage Proceedings Article
In: pp. U333, 2005, ISSN: 0009-7322, (78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, NOV 13-16, 2005).
Activation of cardiac stem-progenitor cells by intramyocardial injection of growth factors regenerate the infarcted heart in pigs Proceedings Article
In: pp. U329-U330, 2005, ISSN: 0009-7322, (78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, NOV 13-16, 2005).
Cardiac stem-progenitor cell activation and ensuing new myocyte formation contribute to the left ventricular physiologic remodeling induced by exercise training Proceedings Article
In: pp. U216, 2005, ISSN: 0009-7322, (78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, NOV 13-16, 2005).