104 entries « 2 of 3 »

2014

Nadal-Ginard, B; Ellison, GM; Torella, D

The cardiac stem cell compartment is indispensable for myocardial cell homeostasis, repair and regeneration in the adult Journal Article

In: STEM CELL RESEARCH, vol. 13, no. 3, B, pp. 615-630, 2014, ISSN: 1873-5061.

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Waring, CD; Vicinanza, C; Papalamprou, A; Smith, AJ; Purushothaman, S; Goldspink, DF; Nadal-Ginard, B; Torella, D; Ellison, GM

The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation Journal Article

In: EUROPEAN HEART JOURNAL, vol. 35, no. 39, SI, pp. 2722-2731, 2014, ISSN: 0195-668X.

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Nadal-Ginard, B; Ellison, GM; Torella, D

Absence of Evidence Is Not Evidence of Absence Pitfalls of Cre Knock-Ins in the c-Kit Locus Journal Article

In: CIRCULATION RESEARCH, vol. 115, no. 4, pp. 415-418, 2014, ISSN: 0009-7330.

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Aquila, I; Vicinanza, C; Scalise, M; Marino, F; Correale, C; Torella, M; Nappi, G; Indolfi, C; Torella, D

Understanding Tissue Repair Through the Activation of Endogenous Resident Stem Cells Book Chapter

In: Humana Press, Cham (Ed.): pp. 31-48, Humana Press, Cham, 2014, ISBN: 978-3-319-03572-7.

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Carresi, C; Aquila, I; Marino, F; Musolino, V; Correale, C; Gliozzi, M; Ellison, GM; Nadal-Ginard, B; Torella, D; Mollace, V

Protection against doxorubicine-induced cardiomyopathy by bergamot polyphenols through myocyte survival and cardiac stem cell activation Journal Article

In: CARDIOVASCULAR RESEARCH, vol. 103, no. 1, 2014, ISSN: 0008-6363, (3rd Congress of the ESC-Council-on-Basic-Cardiovascular-Science on Frontiers in Cardio Vascular Biology, Barcelona, SPAIN, JUL 04-06, 2014).

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Torella, D; Ellison, GM; Torella, M; Vicinanza, C; Aquila, I; Iaconetti, C; Scalise, M; Marino, F; Henning, BJ; Lewis, FC; Gareri, C; Lascar, N; Cuda, G; Salvatore, T; Nappi, G; Indolfi, C; Torella, R; Cozzolino, D; Sasso, FC

Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy Journal Article

In: Journal of the American Heart Association, vol. 3, no. 2, pp. e000434, 2014.

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2013

Ellison, GM; Vicinanza, C; Smith, AJ; Aquila, I; Leone, A; Waring, CD; Henning, BJ; Stirparo, GG; Papait, R; Scarfo, M; Agosti, V; Viglietto, G; Condorelli, G; Indolfi, C; Ottolenghi, S; Torella, D; Nadal-Ginard, B

Adult c-kit(pos) Cardiac Stem Cells Are Necessary and Sufficient for Functional Cardiac Regeneration and Repair Journal Article

In: CELL, vol. 154, no. 4, pp. 827-842, 2013, ISSN: 0092-8674.

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Koudstaal, S; Bastings, MMC; Feyen, DAM; Waring, CD; Torella, D; Sluijter, JPG; Nadal-Ginard, B; Dankers, PYW; Ellison, GM; Chamuleau, SAJ

Sustained delivery of insulin-like growth factor-1/hepatocyte growth factor promotes endogenous cardiac repair and regeneration in the chronic ischemic heart Proceedings Article

In: pp. 277, 2013, ISSN: 0195-668X, (Congress of the European-Society-of-Cardiology (ESC), Amsterdam, NETHERLANDS, AUG 31-SEP 04, 2013).

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Koudstaal, S; Bastings, M; Ellison, GM; Feyen, D; Waring, C; Torella, D; Meijer, B; Sluijter, J; Nadal-Ginard, B; Doevendans, P; Dankers, P; Chamuleau, S

Sustained delivery of Insulin-Like Growth Factor-1/Hepatocyte Growth Factor promotes endogenous cardiac repair and regeneration in the chronic ischemic heart Proceedings Article

In: pp. E1141, 2013, ISSN: 0735-1097, (62nd Annual Scientific Session of the American-College-of-Cardiology, San Francisco, CA, MAR 09-11, 2013).

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2012

Ellison, GM; Polvdorou, J; Mercaldi, R; Burdina, A; Vicinanza, C; Theologou, T; Oo, A; Kuduvalli, M; Wright, DJ; Field, M; Nadal-Ginard, B; Torella, D

Aging and Senescence of Endogenous Cardiac Stem Cells (eCSCs) Determines Their Growth and Differentiation Potential Proceedings Article

In: 2012, ISSN: 0009-7322.

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Torella, D; Aquila, I; Vicinanza, C; Leone, A; Bochicchio, A; Correale, C; Waring, C D; Indolfi, C; Nadal-Ginard, B; Ellison, GM

Resident c-kit-positive Cardiac Stem Cells Replenish Cardiomyocytes During Physiological Cardiac Growth Proceedings Article

In: 2012, ISSN: 0009-7322.

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Ellison, GM; Nadal-Ginard, B; Torella, D

Optimizing Cardiac Repair and Regeneration Through Activation of the Endogenous Cardiac Stem Cell Compartment Journal Article

In: JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, vol. 5, no. 5, SI, pp. 667-677, 2012, ISSN: 1937-5387.

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Leone, A; Aquila, I; Vicinanza, C; Iaconetti, C; Bochicchio, A; Ottolenghi, S; Indolfi, C; Nadal-Ginard, B; Ellison, GM; Torella, D

c-kit-positive cardiac stem cells regulate physiological myocardial cell turnover and are not of bone marrow origin in the adult life Proceedings Article

In: pp. S46, 2012, ISSN: 0008-6363, (2nd Congress of the European-Society-of-Cardiology Council on Basic Cardiovascular Science - Frontiers in Cardiovascular Biology, London, ENGLAND, MAR 30-APR 01, 2012).

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Smith, AJ; Ellison, GM; Waring, CD; Purushothaman, S; Torella, D; Nadal-Ginard, B

Activity status of resident adult cardiac stem cells determines their stem cell properties and growth kinetics Proceedings Article

In: pp. S15-S16, 2012, ISSN: 0008-6363, (2nd Congress of the European-Society-of-Cardiology Council on Basic Cardiovascular Science - Frontiers in Cardiovascular Biology, London, ENGLAND, MAR 30-APR 01, 2012).

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Waring, CD; Papalamprou, A; Purushothaman, S; Smith, AJ; Vicinanza, C; Goldspink, DF; Nadal-Ginard, B; Torella, D; Ellison, GM

Endogenous cardiac stem cell (eCSC) activation, myogenesis and angiogenesis contribute to cardiac remodelling following intensity-controlled exercise training Proceedings Article

In: pp. S16, 2012, ISSN: 0008-6363, (2nd Congress of the European-Society-of-Cardiology Council on Basic Cardiovascular Science - Frontiers in Cardiovascular Biology, London, ENGLAND, MAR 30-APR 01, 2012).

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Ellison, GM; Waring, CD; Vicinanza, C; Torella, D

Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms Journal Article

In: HEART, vol. 98, no. 1, pp. 5-10, 2012, ISSN: 1355-6037.

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2011

Torella, D; Iaconetti, C; Catalucci, D; Ellison, GM; Leone, A; Waring, CD; Bochicchio, A; Vicinanza, C; Aquila, I; Curcio, A; Condorelli, G; Indolfi, C

MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch In Vitro and Vascular Remodeling In Vivo Journal Article

In: CIRCULATION RESEARCH, vol. 109, no. 8, pp. 880-U146, 2011.

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Ellison, GM; Torella, D; Dellegrottaglie, S; Perez-Martinez, C; de Prado, A Perez; Vicinanza, C; Purushothaman, S; Galuppo, V; Iaconetti, C; Waring, CD; Smith, AJ; Torella, M; Ramon, CC; Gonzalo-Orden, JM; Agosti, V; Indolfi, C; Galinanes, M; Fernandez-Vazquez, F; Nadal-Ginard, B

Endogenous Cardiac Stem Cell Activation by Insulin-Like Growth Factor-1/Hepatocyte Growth Factor Intracoronary Injection Fosters Survival and Regeneration of the Infarcted Pig Heart Journal Article

In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 58, no. 9, pp. 977-986, 2011, ISSN: 0735-1097.

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Galuppo, V; Ellison, GM; Vicinanza, C; Aquila, I; Iaconetti, C; Waring, C; Smith, AJ; Indolfi, C; Nadal-Ginard, B; Torella, D

Roles of Wnt/beta-catenin and Tgf-Beta1/Smad2 signaling pathways in endogenous resident c-kit-positive cardiac stem cell proliferation and cardiomyogenic specification in vitro Proceedings Article

In: pp. 957, 2011, ISSN: 0195-668X.

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Leone, A; Ellison, GM; Aquila, I; Vicinanza, C; Iaconetti, C; Waring, C; Ottolenghi, S; Indolfi, C; Nadal-Ginard, B; Torella, D

Adult myocardial cell regeneration originates from and is the progeny of endogenous resident c-kit-positive/CD45-negative cardiac stem cells Proceedings Article

In: pp. 957, 2011, ISSN: 0195-668X.

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Ellison, GM; Torella, D; Leone, A; Smith, AJ; Waring, CD; Curcio, A; Indolfi, C; Nadal-Ginard, B

Resident adult cardiac stem cells fulfil Koch's postulates as the causative agents for myocardial regeneration and homeostasis Proceedings Article

In: pp. 959, 2011, ISSN: 0195-668X.

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2010

Smith, AJ; Ellison, GM; Waring, CD; Purushothaman, S; Torella, D; Nadal-Ginard, B

Resident Adult Rat Cardiac Stem Cells Fulfill Koch's Postulates as the Causative Agents for Myocardial Regeneration and Homeostasis Proceedings Article

In: 2010, ISSN: 0009-7322.

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Waring, CD; Papalambrou, A; Sharp, L; Smith, AJ; Purushothaman, S; Vicinanza, C; Goldspink, D; Torella, D; Nadal-Ginard, B; Ellison, GM

Cardiac Stem Cell Activation and Ensuing Myogenesis and Angiogenesis Contribute to Cardiac Adaptation following Intensity-Controlled Exercise Training Proceedings Article

In: 2010, ISSN: 0009-7322.

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2009

Torella, D; Ellison, GM; Vicinanza, C; Aquila, I; Waring, C; Galuppo, V; Iaconetti, C; Luposella, M; Indolfi, C; Nadal-Ginard, B

Distinct Roles of Wnt/beta-catenin and TGF-beta 1/Smad2 Signaling in Adult Cardiac Stem Cell Expansion and Specification in vitro Proceedings Article

In: pp. S809, 2009, ISSN: 0009-7322, (82nd Scientific Session of the American-Heart-Association, Orlando, FL, NOV 14-18, 2009).

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Torella, D; Ellison, GM; Vicinanza, C; Galuppo, V; Mendicino, I; Aquila, I; Torella, M; Cotrufo, M; Indolfi, C; Nadal-Ginard, B

c-kit+/cd45-cardiac stem cells generate polygonal stromal cells and secrete myxoid matrix in atrial myxomas Proceedings Article

In: pp. 152-153, 2009, ISSN: 0195-668X.

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Ellison, GM; Torella, D; Perez-Martinez, C; Perez, A; Purushothaman, S; Vicinanza, C; Galuppo, V; Agosti, V; Fernandez, F; Nadal-Ginard, B

In situ activation of endogenous cardiac stem cells by intra-coronary administration of IGF-1 and HGF induces myocardial survival and regeneration in the infarcted pig myocardium Proceedings Article

In: pp. 459, 2009, ISSN: 0195-668X.

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Ellison, GM; Torella, D; Trigueros, C; Gonzalez, A; Waring, C; Perez-Martinez, C; Perez, A; Indolfi, C; Fernandez, F; Nadal-Ginard, B

Use of heterologous non-matched Cardiac Stem Cells (CSCs) without immunosuppression as an effective regenerating agent in a porcine model of acute myocardial infarction Proceedings Article

In: pp. 495, 2009, ISSN: 0195-668X.

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Thijssen, DHJ; Torella, D; Hopman, MTE; Ellison, GM

The role of endothelial progenitor and cardiac stem cells in the cardiovascular adaptations to age and exercise Journal Article

In: FRONTIERS IN BIOSCIENCE, vol. 14, pp. 4685-4702, 2009, ISSN: 1093-9946.

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2008

Torella, D; Ellison, GM; Galuppo, V; Vicinanza, C; Mendicino, I; Torella, M; Cotrufo, M; Viglietto, G; Indolfi, C; Nadal-Ginard, B

Cardiac atrial myxomas originate from c-kit+/ flk-1+/Isl-1+/ Nkx2.5+cardiac stem and progenitor cells Proceedings Article

In: pp. 527, 2008, ISSN: 0195-668X.

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Ellison, GM; Torella, D; Purushothaman, S; Nadal-Ginard, B

Cardiomyogenesis from adult cardiac stem cells in response to the morphogens of the developing heart Proceedings Article

In: pp. 896, 2008, ISSN: 0195-668X.

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2007

Torella, D; Ellison, GM; Gasparri, C; Leone, A; Cavaliere, A L; Boncompagni, D; Curcio, A; Indolfi, C; Goldspink, DF; Nadal-Ginard, B

Cardiac stem cell ablation worsens cardiac remodeling and increases mortality after diffuse myocardial damage in rats Proceedings Article

In: pp. 228, 2007, ISSN: 0195-668X.

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Ellison, GM; Torella, D; Karakikes, I; Purushothaman, S; Curcio, A; Gasparri, C; Indolfi, C; Cable, TN; Goldspink, DF; Nadal-Ginard, B

Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells Journal Article

In: JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 282, no. 15, pp. 11397-11409, 2007, ISSN: 0021-9258.

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Torella, D; Ellison, GM; Karakikes, I; Nadal-Ginard, B

Resident cardiac stem cells Journal Article

In: CELLULAR AND MOLECULAR LIFE SCIENCES, vol. 64, no. 6, pp. 661-673, 2007, ISSN: 1420-682X.

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2006

Ellison, GM; Torella, D; Karakikes, I; Curcio, A; Indolfi, C; Goldspink, DF; Nadal-Ginard, B

Cardiac stem cell ablation blocks regeneration, exacerbates cardiac remodeling and increases mortality after diffuse myocardial injury. Proceedings Article

In: pp. 16, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).

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Torella, D; Ellison, GM; Karakikes, I; Galuppo, V; Serio, D De; Onorati, F; Mastroroberto, P; Renzulli, A; Indolfi, C; Nadal-Ginard, B

Biological properties and regenerative potential, in vitro and in vivo, of human cardiac stem cells isolated from each of the four chambers of the adult human heart Proceedings Article

In: pp. 87, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).

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Ellison, GM; Torella, D; Karakikes, I; Perez-Martinez, C; Perez, A

The pig heart harbors cardiac stem-progenitor cells which respond to increasing growth factor stimulation regenerating the infarcted myocardium Proceedings Article

In: pp. 99, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).

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Ellison, GM; Torella, D; Karakikes, L; Nadal-Ginard, B

Molecular signalling pathway determining cardiac stem cell fate Proceedings Article

In: pp. 188-189, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).

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Torella, D; Ellison, GM; Karakikes, I; Curcio, A; Alessio, A; Leone, A; Galuppo, V; Surace, FC; Nadal-Ginard, B; Indolfi, C

Statins foster cardiac stem cell activation and new myocyte formation after acute neurohumoral overload Proceedings Article

In: pp. 209, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).

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Ellison, GM; Torella, D; Karakikes, L; Goldpink, DF; Nadal-Ginard, B

Myocardial damage induces a growth factor Para/Autocrine loop in the spared myocytes which fosters cardiac stem cell activation and ensuing myocyte regeneration Proceedings Article

In: pp. 298, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).

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Torella, D; Ellison, GM; Karakikes, L; Nadal-Ginard, B

The cardiac stem cell: The adult mammalian heart harbours oct-4(pos) cardiac stem cells with very broad developmental potential Proceedings Article

In: pp. 303, 2006, ISSN: 0009-7322, (79th Annual Scientific Session of the American-Heart-Association, Chicago, IL, NOV 12-15, 2006).

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Torella, D; Ellison, GM; Alessio, A; Canepa, A; Surace, FC; Curcio, A; Nadal-Ginard, B; Indolfi, C

HMG-CoA reductase inhibitors enhance cardiac stem-progenitor cell activation and new myocyte formation after diffuse myocardial damage Proceedings Article

In: pp. 18, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).

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Ellison, GM; Torella, D; Nadal-Ginard, B

Wnt signaling and the polycomb-group gene Bmi-1 modulate cardiac stem cell fate Proceedings Article

In: pp. 20, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).

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Torella, D; Ellison, GM; Galuppo, V; Serio, D De; Onorati, F; Renzulli, A; Indolfi, C; Nadal-Ginard, B

Human Cardiac Stem Cells: reproducible isolation and functional characterization of their in vitro and in vivo biological properties and regenerative potential Proceedings Article

In: pp. 161, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).

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Torella, D; Ellison, GM; Leone, A; Serio, D De; Galuppo, V; Goldspink, DF; Nadal-Ginard, B; Indolfi, C

Exercise training activates cardiac stem/progenitor cells through the induction of growth factor production by the myocardium Proceedings Article

In: pp. 444, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).

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Ellison, GM; Torella, D; Ibanez, B; Fernandez, F; Perez-Martinez, C; Perez, A; Badimon, JJ; Nadal-Ginard, B

The pig heart harbors cardiac stem-progenitor cells which respond to growth factor stimulation regenerating the infarcted myocardium Proceedings Article

In: pp. 546-547, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).

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Torella, D; Ellison, GM; Nadal-Ginard, B

Cardiac stem cells expressing the pluripotency marker Oct-4 are present in the adult mammalian heart Proceedings Article

In: pp. 552, 2006, ISSN: 0195-668X, (28th Congress of the European-Society-of-Cardiology/World Congress of Cardiology, Barcelona, SPAIN, SEP 02-06, 2006).

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Torella, D; Ellison, GM; Dellegrottaglie, S

Testing regeneration of human myocardium without knowing the identity and the number of effective bone marrow cells transplanted: Are the results meaningful? Journal Article

In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 48, no. 2, pp. 417, 2006, ISSN: 0735-1097.

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2005

Ellison, GM; Torella, D; Leone, A; Ibanez, B; Mendez-Ferrer, S; Indolfi, C; Goldspink, DF; Nadal-Ginard, B

Cardiac stem-progenitor cell resistance to hyper-adrenergic stimulation produces rapid left ventricular function recovery after isoproterenol-induced diffuse myocardial damage Proceedings Article

In: pp. U333, 2005, ISSN: 0009-7322, (78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, NOV 13-16, 2005).

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Ellison, GM; Torella, D; Ibanez, B; Mendez-Ferrer, S; Fernandez, F; Perez-Martinez, C; Perez, A; Nadal-Ginard, B

Activation of cardiac stem-progenitor cells by intramyocardial injection of growth factors regenerate the infarcted heart in pigs Proceedings Article

In: pp. U329-U330, 2005, ISSN: 0009-7322, (78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, NOV 13-16, 2005).

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Torella, D; Ellison, GM; Leone, A; Serio, D De; Cavaliere, AL; Canepa, A; Alessio, A; Stillo, A; Nadal-Ginard, B; Indolfi, C

Cardiac stem-progenitor cell activation and ensuing new myocyte formation contribute to the left ventricular physiologic remodeling induced by exercise training Proceedings Article

In: pp. U216, 2005, ISSN: 0009-7322, (78th Annual Scientific Session of the American-Heart-Association, Dallas, TX, NOV 13-16, 2005).

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104 entries « 2 of 3 »